Acta Dermato-Venereologica 99-7CompleteContent | Page 31

711 Vulvar Dyschromia in a Child: A Quiz Caroline DE LORENZI, Gürkan KAYA, Sandrine QUENAN and Anne-Marie CALZA Division of Dermatology and Venereology, Geneva University Hospitals, rue Gabrielle-Perret-Gentil 4, CH-1205 Genève, Switzerland. E-mail: [email protected] A 7-year-old Eritrean girl presented with a 2-year history of asymptomatic skin lesions that had appeared progressi- vely on her buttocks and genital area. She had no previous personal or familial medical history. Clinical examination revealed hypopigmented macules and small slightly brow- nish papules on the pubis and inner side of her thighs (Fig. 1 a,b). Initially, an inflammatory papilloma virus (HPV) infection was suspected. A skin biopsy revealed a slight epidermal hyperplasia with pigmentation of the basal cell layer and a focal loss of melanocytes (Fig. 1c). Moderate hyperkeratosis was observed. PCR for HPV was negative. What is your diagnosis? See next page for answer. Fig. 1. (a) Hypopigmented macules and brownish papules on the pubis and inner side of the thighs in a 7-year-old girl. (b) Close-up of hypopigmented and brownish papules on the inner side of the thighs. (c) Moderate hyperkeratosis, slight epidermal hyperplasia and focal loss of melanocytes (haematoxylin and eosin (H&E), original magnification ×10). QUIZ SECTION This is an open access article under the CC BY-NC license. www.medicaljournals.se/acta Journal Compilation © 2019 Acta Dermato-Venereologica. doi: 10.2340/00015555-3191 Acta Derm Venereol 2019; 99: 711–712