Acta Dermato-Venereologica 99-10CompleteContent | Page 32

SHORT COMMUNICATION 933 Satisfaction with Information Provision and Health-related Quality of Life in Basal and Squamous Cell Carcinoma Patients: A Cross-sectional Population-based Study Rick WAALBOER-SPUIJ 1 , Loes M. HOLLESTEIN 1,2 , Tamar E. C. NIJSTEN 1 and Lonneke V. VAN DE POLL-FRANSE 2–4 ; on behalf of the BaSQoL Group 1 Department of Dermatology, Erasmus MC University Medical Centre, Postbus 2040, NL-3000 CA, Rotterdam, 2 Department of Research, Netherlands Comprehensive Cancer Organization (IKNL), Utrecht, 3 CoRPS - Centre of Research on Psychology in Somatic diseases, Department of Medical and Clinical Psychology, Tilburg University, Tilburg, and 4 Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands. E-mail: [email protected] Accepted May 22, 2019; E-published May 23, 2019 The incidence of keratinocytic carcinomas (KC) (basal cell carcinoma (BCC) and squamous cell carcinoma (SCC)) is high and further increasing. It is important to identify patients with high disease burden (1, 2). The Basal and Squamous Cell Carcinoma Quality of Life (BaSQoL) questionnaire was developed to measure disease specific Health-Related Quality of Life (HRQoL) (3). In other can- cer patients it was shown that better information provision is associated with better HRQoL (4). Information provi- sion is an important aspect of supportive care: increasing knowledge about disease and treatment leads to better illness perception, which could lead to a better HRQoL (5). This relation has not been described in KC patients, and may differ from other cancers, due to low mortality and low impact treatment. This study aims to assess the satisfaction with received information and the association with HRQoL in population-based sample of KC patients in the Netherlands. We hypothesized that, patients satisfied with received information report a better HRQoL. specific quality of life was measured by the EORTC QLQ-Core 30 (EORTC QLQ-C30) (8). The disease-specific BaSQoL has 5 subscales (3). Higher scores implicate a higher HRQoL impact. The self-reported comorbidity questionnaire measured comorbidity (9). Statistical analyses Mean values were compared with independent sample t-tests bet- ween patients who were satisfied and dissatisfied with information. Bar charts display the BaSQoL and EORTC QLQ-C30 subscales, stratified by satisfaction with information provision. The associa- tion between HRQoL (outcome) and satisfaction with information (covariate) was assessed with multivariable linear regression ana- lysis. Other a priori selected covariates included: age, time since diagnosis, sex, education, occupation, partnership, comorbidity, and type of tumour. Multiple imputations (n = 25) were used to ac- count for the missing data (all covariates and outcomes included). Multiple linear regression assumptions were met. p-values < 0.05 (two-sided) from regression models were con- sidered statistically significant. All other p-values were corrected (Benjamini-Hochberg procedure) and considered statistically significant if p < 0.033 (two-sided) (10). Analyses were performed in SPSS, Version 21.0 (Armonk, New York: IBM Corporation). METHODS RESULTS A cross-sectional study was performed among 1,173 patients, selec- ted from the Southern region of the population-based Netherlands Cancer Registry (NCR). Data were collected during the validation of the BaSQoL (3, 6). Socio-demographic data were collected and disease specific data were gathered from the NCR. Unfortunately, there were no data on the provided information available. Satisfaction with the information provision was measured with the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire INFO25 (EORTC QLQ-INFO25) (7). For this study, the 4-point Likert scale of the item ‘satisfaction with information provision’ was dichotomized into satisfied (‘quite a bit’ – ‘very much’) and dissatisfied (‘not at all’ – ‘a little’). Cancer- Of the 1,173 patients, 721 (61%) completed the ques- tionnaire. Patient and tumour characteristics are shown in Table SI 1 . There was no difference in satisfaction with information in tumour type (BCC vs SCC) or BCC subtype, facial tumour, not having a partner and having more comorbidities (Table SI 1 ). Thirty-seven percent (84/225) dissatisfied and 7% (28/416) satisfied patients indicated that they had wanted more informa- tion about skin cancer in general, causes, treatment, follow-up and how to recognize new lesions. Three percent (n = 24) wanted less information. The information received was considered helpful in 68% (n = 417). HRQoL was statistically significantly lower among patients who were dissatisfied with information provision (Fig. 1). Satisfaction with information provision was associated with behaviour, diagnosis and treat­ ment, worries and appearance BaSQoL subscales with negative beta values (–0.3 to –0.1), indica- Fig. 1. Mean with standard error. Basal and squamous cell carcinoma quality of life (a) and European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-C30 subscale scores and satisfaction with information provision (b). This is an open access article under the CC BY-NC license. www.medicaljournals.se/acta Journal Compilation © 2019 Acta Dermato-Venereologica. doi: 10.2340/00015555-3226 Acta Derm Venereol 2019; 99: 933–934