Acta Dermato-Venereologica 97-10CompleteContent | Page 34

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Bone Formation in Cutaneous Nodules on the Leg: A Quiz
Ferdinand TOBERER, Alexander H. ENK, Wolfgang HARTSCHUH and Jessica HASSEL
Department of Dermatology, Venereology and Allergology, University Medical Center, Ruprecht-Karls-University, Im Neuenheimer Feld 440,
DE-69120 Heidelberg, Germany. E-mail: [e-mail]
A 74-year-old man presented with several weeks’ history
of multiple cutaneous nodules and plaques on his right leg
(Fig. 1a). Histopathology revealed infiltrating epithelioid,
hyperchromatic and pleomorphic tumour cells, mainly
arranged in strands. In addition, there were areas of bony
trabeculae rimmed by neoplastic cells (Fig. 1b). Ten months
QUIZ SECTION
previously the patient had been diagnosed with an ulcerated
acral lentiginous melanoma of his right hallux, measuring 14
mm in depth. Amputation of the hallux and inguinal lymph
node dissection were performed as the sentinel lymph node
was positive.
What is your diagnosis? See next page for answer.
Fig. 1. (a) Right thigh with multiple cutaneous nodules and plaques. (b)
Punch biopsy of the nodules revealing areas with bony trabeculae rimmed
by neoplastic cells (haematoxylin-eosin, original magnification ×100).
This is an open access article under the CC BY-NC license. www.medicaljournals.se/acta
Journal Compilation © 2017 Acta Dermato-Venereologica.
doi: 10.2340/00015555-2754
Acta Derm Venereol 2017; 97: 1263–1264