ISCHEMIC HEART DISEASE
VALVE DISEASE
CARDIAC RHYTHM DISORDERS
HEART FAILURE
CLINICAL TRIALS
CLINICAL TRIALS
ISCHEMIC HEART DISEASE
Trial : Define GPS PI : Mustafa Ahmed , M . D . Brief Synopsis : Distal Evaluation of Functional Performance with Intravascular Sensors to Assess the Narrowing Effect : Guided Physiologic Stenting
Trial : Protect IV Trial PI : Mustafa Ahmed , M . D . Brief Synopsis : Impella ® -Supported PCI in High-Risk Patients with Complex Coronary Artery Disease and Reduced Left Ventricular Function : The PROTECT IV Trial
Trial : SOS AMI PI : Hussein Abu Daya , M . D . Brief Synopsis : Selatogrel Outcome Study in Suspected Acute Myocardial Infarction ( SOS-AMI )
VALVE DISEASE
Trial : Expand II PI : Mustafa Ahmed , M . D . Brief Synopsis : Evolut™ EXPAND TAVR II Pivotal Trial
Trial : APOLLO PI : Mustafa Ahmed , M . D . Brief Synopsis : Transcatheter Mitral Valve Replacement with the Medtronic Intrepid™ TMVR System in Patients with Severe Symptomatic Mitral Regurgitation – APOLLO Trial
Trial : MOMENTIS PI : James Davies , M . D . Brief Synopsis : A Prospective , Global Study Designed to Collect Real-World Clinical Outcomes of the MITRIS RESILIA Mitral Valve – North America ( MOMENTIS )
CARDIAC RHYTHM DISORDERS
Trial : HEAL LAA PI : Tom McElderry , M . D . Brief Synopsis : Post-Market Real World Outcomes in WATCHMAN FLX™ Pro Left Atrial Appendage Closure ( LAAC ) Device
Trial : AIM Higher PI : Ruchit Shah , M . D . Brief Synopsis : Assessment of Implantable CCM in the Heart Failure Group with Higher Ejection Fraction
Trial : Smartpulse PI : Tom McElderry , M . D . Brief Synopsis : Safety and Effectiveness Evaluation of the THERMOCOOL SMARTTOUCH™ SF Catheter with the TRUPULSE™ Generator for Treatment of Drug Refractory Symptomatic Paroxysmal Atrial Fibrillation ( PAF )
HEART FAILURE
Trial : Respira PI : Jose Tallaj , M . D . Brief Synopsis : A Phase 2 , Open-label , Dose Escalation Study to Evaluate the Safety and Efficacy of RT234 on Exercise Parameters Assessed by Cardiopulmonary Exercise Testing ( CPET ) in Subjects with Pulmonary Arterial Hypertension ( PAH )
Trial : REBIRTH PI : Gretchen Wells , M . D . Brief Synopsis : Randomized Evaluation of Bromocriptine in Myocardial Recovery Therapy ( REBIRTH ) for Peripartum Cardiomyopathy
Trial : ODYSSEY PI : Jose Tallaj , M . D . Brief Synopsis : A Randomized , Double-blind , Placebo-controlled Clinical Study to Evaluate Mavacamten in Adults with Symptomatic Nonobstructive Hypertrophic Cardiomyopathy
28 UAB Cardiovascular Institute 2023 Annual Report