16 Understanding the Biology of Parkinson’ s
PPMI: A United Effort to Predict and Prevent Parkinson’ s
For the past decade, thousands of patients, scientists and volunteers have contributed to MJFF’ s landmark Parkinson’ s Progression Markers Initiative( PPMI) study.
A cornerstone of our efforts to increase biological understanding of the disease and its symptoms, PPMI is a peerless endeavor to funnel insights, practical tools and data directly into today’ s drug development environment. In turn, human studies of the disease increase our understanding of biology and open new avenues of scientific inquiry to speed nextgeneration strategies to eradicate the disease once and for all.
In 2021, PPMI entered its next phase: enrolling people newly diagnosed with Parkinson’ s as well
$ 102.2M invested in PPMI since 2010
as those who may be at risk for the disease. By growing the study from 1,500 to 4,000 participants, taking part at nearly 50 sites in 12 countries, and enrolling as many as 100,000 people online, we hope to gain critical information about who gets the disease, who doesn’ t, and why.