2021 Year in Review | Page 12

10 Transforming the Drug Development Landscape

Tapping into a Promising LRRK2 Pipeline

2012 Companies Develop Drugs and Test in Lab
2017 First In-human LRRK2 Trials Begin
2013 LRRK2 Safety Initiative Proves Safe to Enter Human Testing *
2018 Study Shows LRRK2 Therapies May be Useful for Wide Parkinson ’ s Population *
2021 Late-stage Trials Begin
* Supported by MJFF Funding
2019 Research Finds Marker of LRRK2 Activity *
2020 Partners Announce $ 1 Billion Deal to Co-develop Denali LRRK2 Drugs