2020 UAB Cardiovascular Institute Annual Report CVI Annual Report 2019-2020 6

A TRADITION OF INNOVATION 1950s 1960s 1950-58 1970s The first heart transplant in Alabama is performed at UAB by Robert Karp, MD John W. Kirklin, MD, moves to UAB from Mayo Clinic to develop a world-class cardiac surgery program that garners national and international recognition 1962 W. Sterling Edwards, MD, performs Alabama’s first cardiac surgery utilizing cardiopulmonary bypass 1966 Tinsley R. Harrison, MD, one of the most influential physicians of the 20th century, appointed the first director of the Division of Cardiovascular Disease 1980s 1981 1967 Champ Lyons, MD, and Tinsley R. Harrison, MD, begin the Cardiovascular Research and Training Program with a grant from the National Heart Lung Institute 1970 UAB’s national and international prominence in cardiovascular services is attributable to the men and women whose thoughts, work, research, and dedication to medicine began in 1950. Our rich history of innovation led to the significant advances in cardiovascular medicine that continue to benefit patients today. Louis Sheppard, PhD, FACMI, and John W. Kirklin, MD, oversee the world’s first computerized ICU that makes use of automated care for cardiac surgery patients 1984 Developed currently used color Doppler techniques for semi-quantitation of mitral, aortic, and tricuspid valve regurgitation severity 1986 The first arterial switch operation in Alabama is performed by Albert Pacifico, MD, who served as director of the Division of Cardiothoracic Surgery from 1984 to 2006 1986 UAB Electrophysiol- ogy began DC ablation of AV node for atrial fibrillation by Neal Kay, MD, and Vance Plumb, MD 1990s 1988 The first heart-lung transplant in the southeast is performed by James K. Kirklin, MD, who served as director of the Division of Cardiothoracic Surgery from 2006 to 2016 1989 First intracoronary stenting was performed at UAB as part of clinical trial for acute or threatened vessel closure during PTCA 1996 1990 First pulmonary vein isolation in Alabama is performed at UAB by Neal Kay, MD, and Vance Plumb, MD The first radio frequency catheter ablation in Alabama was performed for Wolff-Parkinson- White syndrome by Vance Plumb, MD 1993 The first double lung transplant in Alabama is performed by David McGiffin, MD, and George Zorn, MD 1989 The first mechanical circulatory support device implant in Alabama is performed by William Holman, MD Building upon decades of excellence in cardiovascular care, the UAB Cardiovascular Institute (CVI) was established in 2019 to enhance cardiovascular service delivery across UAB Medicine. Among the largest cardiovascular centers in the country, the CVI aligns the clinical specialties of cardiology, cardiac surgery, vascular surgery, and cardiothoracic anesthesia to deliver optimal care to patients with cardiovascular- related conditions. We are at the forefront of advances in the treatment of cardiovascular disease, and our program is consistently listed among the top cardiovascular centers in the nation. 2 UAB Cardiovascular Institute Annual Report 2000s 1997 First endovascular aneurysm repair (EVAR) in Alabama is performed at UAB by William D. Jordan, MD 2007 The world’s first infant with a single ventricle to be successfully bridged to heart transplant with a Berlin Heart is performed by James K. Kirklin, MD 2009 First robotic lung resection in Alabama is performed at UAB by Robert Cerfolio, MD, who is internationally known as an innovator in the field of robotic surgery 2011 Sumanth Prabhu, MD, is appointed the 8th director of the UAB Division of Cardiovascular Disease and establishes the UAB Comprehensive Cardiovascular Center to advance multidisciplinary cardiovascular research 2012 2013 First transcatheter aortic valve replacement (TAVR) in the state of Alabama is performed by James Davies, MD, and Massoud Leesar, MD, in a collaboration between the divisions of Cardiothoracic Surgery and Cardiovascular Disease The Alabama Adult Congenital Heart Program is established as a collaboration among the divisions of Cardiovascular Disease, Pediatric Cardiology, and Cardiothoracic Surgery 2012 First subcutaneous implantable cardioverter- defibrillator (ICD) placement at UAB First percutaneous paravalvular periprosthetic leak closure in Alabama performed at UAB by Oluseun Alli, MD 2014 2016 First endovascular thoracoabdominal aneurysm repair using customized branched/ fenestrated device is performed at UAB by Adam W. Beck, MD 2017 UAB became the first center in Alabama to be certified for the total artificial heart (Syncardia) and performs first such implant in Alabama 2017 2016 UAB first in Alabama to offer dissolving heart stent First in Alabama to implement new FDA- approved Amplatzer PFO Occluder 2017 Opening of specialized Women’s Heart Health clinic 2019 Established UAB Cardiovascular Institute Currently, UAB Medicine is Alabama’s only: • Major referral center for complex cardiac and vascular disorders • Hospital offering heart and lung transplantation and long-term mechanical circulatory support • Facility that performs complex congenital heart surgeries • Group with unique multidisciplinary cardiovascular programs, including pregnancy and heart disease, cardio-oncology, pulmonary hypertension, pharmacogenomics, and refractory hypertension In addition to our focus on patient care, we provide an environment that supports comprehensive training programs for health professionals and promotes clinical, basic, and outcomes research to further medical science and improve outcomes for patients. The UAB Cardiovascular Institute has been listed among U.S. News & World Report’s (USNWR) “Top 50 Centers for Cardiology and Heart Surgery” for the last several years. In its 2019 rankings, USNWR also recognized UAB Medicine for our performance in several key clinical areas, including heart bypass surgery, heart valve surgery, heart failure, lung cancer surgery, and abdominal aortic surgery. uabmedicine.org 3

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