2020 UAB Cardiovascular Institute Annual Report CVI Annual Report 2019-2020 6 | Page 26

The UAB Vein Program is the most comprehensive venous disease-based service in Alabama and has become an important resource for both straightforward and complex vein problems. The program provides comprehensive evaluation and specialized treatment for vein disorders, such as acute and chronic deep venous thrombosis (DVT), venous ulcers, iliac vein and vena cava obstruction, oncologic venous reconstructions, and rare disorders of the venous system, such as venous malformations. The UAB Vein Clinic is the outpatient arm of the larger UAB Vein Program. Many minor vein procedures can be performed in an outpatient setting, including saphenous vein ablation and treatment of spider and varicose veins, with few side effects and minimal scarring. The Comprehensive Vein Clinic is one of only a few facilities in Alabama accredited by the Intersocietal Accreditation Commission for Vein Centers. HIGHLIGHTS • High volume of acute and chronic DVT treatments • Removal of chronically indwelling inferior vena cava (IVC) filters • Complex minimally invasive outpatient venous procedures can be performed at the UAB Vein Clinic, including: – Veinwave system, which uses heat to close the veins and render them nearly invisible – Sclerotherapy, in which a liquid chemical is injected into the vein that causes it to collapse and fade – Endovenous ablation, which closes off the blood supply to the affected veins – Microphlebectdomy, in which varicose veins or vein clusters are removed through tiny incisions Significant post-thrombotic syndrome due to complete IVC filter, vena cava, and iliofemoral vein thrombotic occlusion. Advanced catheter clot removal using phamacomechanical thrombectomy techniques, along with filter removal, resulted in restored patency to IVC and iliofemoral vein system and significant clinical improvement. 24 UAB Cardiovascular Institute Annual Report PERIPHERAL ARTERIAL & VENOUS DISEASE RESEARCH HIGHLIGHTS: • Multiple innovative device and drug trials are ongoing for new treatments of peripheral arterial disease. • An active participant in research and clinical trials for the diagnosis and treatment of peripheral arterial disease. These studies include the multi-institutional, NIH-sponsored BEST-CLI trial (Best Endovascular vs. Best Surgical Therapy in Patients with Critical Limb Ischemia), which evaluates and compares the outcomes of open and minimally invasive treatments performed for limb salvage. • Physicians in the UAB Stroke Center participate in the CREST 2 trial, which is evaluating medical therapy for asymptomatic carotid stenting or carotid endarterectomy. • UAB Medicine surgeons participate in the Society for Vascular Surgery Vascular Quality Initiative (SVS VQI), allowing evaluation for outcomes and national/regional benchmarking of outcomes and care processes. COMPREHENSIVE VEIN PROGRAM SELECTED PUBLICATIONS • Gagne PJ, Gasparis A, Black S, Thorpe P, Passman M, Vedantham S, Marston W, Iafrati M. Analysis of threshold stenosis by multiplanar venogram and intravascular ultrasound examination for predicting clinical improvement after iliofemoral vein stenting in the VIDIO trial. J Vasc Surg Venous Lymphat Disord. 2018 Jan;6(1):48-56.e1. doi: 10.1016/j.jvsv.2017.07.009 • Parmar GM, Novak Z, Spangler E, Patterson M, Passman MA, Beck AW, Pearce BJ. Statin use improves limb salvage after intervention for peripheral arterial disease. J Vasc Surg. 2019 Aug;70(2):539-546. doi: 10.1016/j.jvs.2018.07.089 • Leithead C, Novak Z, Spangler E, Passman MA, Witcher A, Patterson MA, Beck AW, Pearce BJ. Importance of postprocedural Wound, Ischemia, and foot Infection (WIfI) restaging in predicting limb salvage. J Vasc Surg. 2018 Feb;67(2):498-505. doi: 10.1016/j.jvs.2017.07.109 • Whaley ZL, Cassimjeea I, Novak Z, Rowland D, Lapollaa P, Chandrashekar A, Pearce BJ, Beck AW, Handa A, Lee R. (In Press) The Spatial Morphology of Intraluminal Thrombus Influences Type II Endoleak After Endovascular Repair of Abdominal Aortic Aneurysms, Annals of Vascular Surgery, Available online 5 August 2019. • Parmar, GM, Novak, Z, Spangler, E, Beck, AW, Pearce, BJ; Zdenek Novak, MD, PhD, MSHI Statin use improves limb salvage after intervention for peripheral arterial disease, Journal of Vascular SurgeryVolume 70, Issue 2, August 2019, Pages 539-546 • Leithead, C, Novak, Z, Spangler, E, Passman, MA, Witcher, A, Patterson, MA, Beck, AW, Pearce, BJ Importance of postprocedural Wound, Ischemia, and foot Infection (WIfI) restaging in predicting limb salvage. Journal of Vascular Surgery, Vol 67, Issue 2, February 2018, Pages 498-505. • Axley J, Novak Z, McFarland G, Spangler EL, Pearce BJ, Patterson MA, Passman MA, Beck AW Informing Telemetry Use in Post-Operative Vascular Surgery Patients Dysrhythmia in the Vascular Quality Initiative. Ann Vasc Surg 2019; 61:20-21 • Wilson R, Novak Z, Spangler EL, McFarland G, Passman MA, Patterson MA, Beck AW Assessing the Relationship Between Post-Operative Myocardial Infarction, Preoperative Hemoglobin and Perioperative Blood Usage. Ann Vasc Surg 2019;21-22 • Rothenberg KA, McFarland GE, Stern JR. Endovascular Repair of a Ruptured Hepatic Artery Pseudoaneurysm Secondary to Fibromuscular Dysplasia. Vasc Endovascular Surg. 2019 Jan;53(1):66-70. • McFarland, G, Tran, K, Virgin-Downey, W, Chandra, V, Mell, M, Harris, EJ, Dalman, RL, Lee, JT. Standard EVAR in patients with dilated infrarenal necks requiring a 34-36mm endograft is associated with increased risk of type 1a endoleak. J Vasc Surg.2019 Feb;69(2):385-393. • Tran K, Lee AM, McFarland GE, Sgroi MD, Lee JT. Complex EVAR is associated with higher peri-operative mortality but not late-mortality compared to infrarenal EVAR amongst octogenarians. J Vasc Surg. 2019 Feb;69(2):327-333. • Luke M Stewart, Benjamin Pearce, Danielle C Sutzko, Graeme E. McFarland, Emily L. Spangler, Zdenek Novak, Adam W. Beck, The Association of Preoperative Length of Stay on Surgical Site Infection After Lower Extremity Bypass. October 2019. uabmedicine.org 25