2020 UAB Cardiovascular Institute Annual Report CVI Annual Report 2019-2020 6

Located at Children’s of Alabama (COA) hospital, UAB’s congenital cardiac surgery program is one of the oldest of its kind in the nation, having been founded in 1966 by one of the fathers of congenital heart surgery, John W. Kirklin, MD. The program continues to enjoy the world-class reputation forged by Dr. Kirklin, thanks to an exceptional team of congenital heart surgeons and intensivists who work closely with pediatric cardiologists in caring for young patients. We provide surgical treatment of every conceivable congenital cardiac condition and show excellent outcomes. STAT mortality categories were developed by the Society of Thoracic Surgeons (STS) and the European Association for Cardiothoracic Surgery as a method to stratify pediatric cardiac surgical operations by risk. These categories allow comparisons among congenital heart surgery programs with regard to results across all levels of surgical complexity. The COA congenital heart surgery program for the Spring 2019 STS Congenital National Database Harvest reports an overall mortality for the last 4 years of 2.1% compared to the National STS mortality of rate of 2.8%. COA received an Overall Quality Star Rating of 2 stars, which is considered not significantly different than the STS mean. COA HIGH-VOLUME CONGENITAL HEART SURGERY CENTER STAT Categories with Volumes and Operative Mortality Last 4 years (2015-2018) STAT 1 Least complex, with lowest risk of mortality Quality rating of 2 stars, not statistically different than the STS mean STAT 5 Most complex, with highest risk of mortality COA 2018 STAT CATEGORIES AND MORTALITY PEDIATRIC CONGENITAL HEART PROCEDURES 2014-2018 Source: STS Spring Harvest 2019, period ended 12/31/19. STS composite Source: UAB STS Congenital Heart Surgery Database 14 UAB Cardiovascular Institute Annual Report UAB HAS SPECIAL PEDIATRIC EXPERTISE IN THE FOLLOWING COMPLEX PROCEDURES: CONGENITAL HEART DISEASE • Arterial switch operation • Childhood valve-sparing aortic root replacement • Complex valve reconstruction • Fontan procedure • Interrupted aortic arch • Norwood • Pediatric transplantation and mechanical circulatory support • Ross procedure SELECTED PUBLICATIONS • Li Q, Hara H, Banks A, Yamamoto T, Ayares D, Mauchley DC, Dabal RJ, Padilla LA, Carlo WF, Rhodes LA, Cooper DKC, Cleveland DC. Anti-Pig antibody in infants: Can a genetically-engineered pig heart bridge to allotransplantation? Ann Thorac Surg. 2019 Sep 30. doi: 10.1016/j.athoracsur.2019.08.061. https://www.ncbi.nlm. nih.gov/pubmed/31580857 • Hurst D, Padilla LA, Walters W, Hunter J, Cooper DK, Cleveland D, Eckhoff D, Paris W. Pediatric Xenotransplantation Clinical Trials and the Right to Withdraw. J Med Ethics. 2019 Nov 8. doi: 10.1136/ medethics-2019-105668. https://www.ncbi.nlm.nih.gov/pubmed/31704780 • Alongi A, Kirklin J, Luqin, Padilla L, Pavnica J, Romp R, Mauchley D, Cleveland D, Dabal R. (In press). Surgical Management of Heterotaxy Syndrome: Current Challenges and Opportunities. World Journal of Pediatric and Congenital Heart Surgery Accepted October 2019. • Carlo WF, Cnota JF, Dabal RJ, and Anderson JB. Practice Trends Over Time in the Care of Infants with Hypoplastic Left Heart Syndrome: A Report from the National Pediatric Cardiology Quality Improvement Collaborative (NPC-QIC). Congenital Heart Disease. 2017 Jan 25. [Epub ahead of print.] • Chatterjee, A., Bajaj, N. S., Mcmahon, W. S., Cribbs, M. G., White, J. S., Mukherjee, A., & Law, M. A. (2017). Transcatheter Pulmonary Valve Implantation: A Comprehensive Systematic Review and Meta Analyses of Observational Studies. Journal of the American Heart Association, 6(8). doi:10.1161/jaha.117.006432 • Miller V, Padilla LA, Schuh A, Mauchley D, Cleveland D, Aburjania Z, Dabal R. Evaluation of Cardiothoracic Surgery Residency and Fellowship Program Websites. 2019 Journal of Surgical Research Volume 246, February 2020, Pages 200-206. https://doi.org/10.1016/j.jss.2019.09.009 • Dabal RJ. Truncus Arteriosus and the Branch Pulmonary Arteries: Joined at the Hip for Life? Semin Thorac Cardiovasc Surg. 2018 Summer; 30(2): 205-206. • Smood B, Kirklin JK, Pavnica J, Tresler M, Johnson WH Jr, Cleveland DC, Mauchley DC, Dabal RJ. Congenitally Corrected Transposition Presenting in the First Year of Life: Survival and Fate of the Systemic Right Ventricle. World J Pediatr Congenit Heart Surg. 2019 Jan;10(1):42-49. PMID: 30760124 • Chatterjee A, Miller NJ, Cribbs MG, Law MA. Transcatheter Repair of Pulmonary Venous Baffle Stenosis. JACC Cardiovasc Interv. 2018 Jul 26. pii: S1936-8798(18)31367-0 • Alten J, Law M, Borasino S, Erwin WC, Cleveland DC. Routine Sildenafil Does Not Improve Clinical Outcomes after Fontan Operation. Pediatric Cardiology. 2018 March, 39(3) 544-645. PMID: 29372280 • Mauchley D, Stiegler J, Padilla L, Zviadi A, Dabal R, Cleveland DC. Repair of Rare Vascular Ring: Circumflex Aortic Arch with Associated Hypoplasia and Coarctation. World Journal for Pediatric and Congenital Heart Surgery. 2019 May 19:2150135119828387. Epub ahead of print. PMID: 31104570. • Osula D, Farris GR, Chatterjee A, Law MA, Cribbs MG. Intra-aortic Balloon Pump As a Bridge to Heart Transplant After Non-ST-Segment-Elevation Myocardial Infarction in Palliated Hypoplastic Left Heart Syndrome. Circ Heart Fail. 2019 Sep;12(9):e006130. doi: 10.1161/CIRCHEARTFAILURE.119.006130 uabmedicine.org 15

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