2019 Novel Coronavirus Pandemic | Page 2

2019 NOVEL CORONAVIRUS TIMELINE DEC 31, 2019 Pneumonia of unknown etiology emerges in Wuhan City, Hubei Province, China. BACKGROUND INFORMATION From December 31, 2019 through January 3, 2020, a total of 44 case-patients with pneumonia of unknown etiology were reported to the World Health Organization (WHO) by national authorities in China. The Chinese quickly isolated a new coronavirus on January 7, 2020, and by January 20th, there were 282 confirmed infected cases. The new virus named SARs CoV-2, was first detected in Wuhan City, Hubei Province, China, and continues to spread throughout the mainland there. Just a little over a month later, this novel coronavirus, infected over 42,000 people in China, causing 1,017 deaths there, and has spread globally causing a pandemic. The first U.S. case was reported on January 22 and subsequently confirmed by the Centers for Disease Control and Prevention (CDC). The illness onset was marked as early as January 14th. By February 10, 2020, there were 13 confirmed cases identified in Washington, California, Arizona, Illinois, and Massachusetts. Currently, all states in the U.S., the District of Columbia, Puerto Rico, Guam, and the U.S. Virgin Islands are affected. JAN 3, 2020 The virus itself, called SARS CoV-2 is a new coronavirus in that it has not been previously recognized in humans. Early cases were thought to have crossed over from an animal, such as a camel, cow, cat, or bat, because many of those that were first infected were exposed to a large seafood and live animal market in Wuhan. The animal source has not yet been identified. COVID-19 is a betacoronavirus like Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV), both of which have their origin in bats. We now know that human to human transmission is occurring. Chinese authorities alert WHO that a group of 44 patients are sick with pneumonia. JAN 7, 2020 The Chinese authorities isolate a new coronavirus. JAN 20, 2020 The official name for the disease caused by SARS CoV-2 is COVID-19. ‘CO’ stands for ‘corona’, ‘VI’ for ‘virus,’ and ‘D’ for ‘disease’. COVID-19 causes respiratory illness with symptoms of fever, cough, and shortness of breath with symptoms ranging from mild, as with the common cold, to deadly. Risk is higher in those individuals over 60 years of age and those with compromised immune systems. The most common laboratory findings among hospitalized patients with pneumonia on admission included leukopenia, leukocytosis, lymphopenia, elevated alanine aminotransferase and aspartate aminotransferase levels. Most patients show bilateral involvement on chest CT. Typically there are multiple areas of consolidation and ground glass opacities. Currently there is no effective vaccine or antiviral agent for this infection, and treatment is supportive to manage symptoms. Clinical management guidelines include information in the following links: 282 cases are confirmed in China. • Surviving Sepsis guidelines for septic shock • WHO interim guidance on clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected JAN 22, 2020 First confirmed case in the U.S. in a patient who traveled from China. APRIL 13, 2020 U.S. confirmed cases: 554,849 U.S. deaths: 21,942 GLOBAL: 1,773,084 cases 111,652 deaths • Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America Corticosteroids should be avoided unless there is an indication to manage conditions such as chronic obstructive pulmonary disease or septic shock, because there is potential for prolonging viral replication as has been observed in MERs-CoV patients. IDENTIFY, ISOLATE, AND INFORM There are several situations which increase the risk of exposure to COVID-19. You are at an elevated risk if you are: • A healthcare worker caring for patients with COVID-19 • Living, working or spending time in communities* which are highly populated and have an intense and ongoing spread of SARS CoV-2 (e.g. New York city, Chicago, New Jersey) • A close contact of someone who has COVID-19, such as family member • A traveler who is returning from international location where there is community spread *You can check the case count in your community by going to your state website and clicking on the county list or state county map. This is an ever-evolving disaster due to new findings and data and availability of resources, so refer to the CDC website for detailed information when you need it. HealthStream.com/contact • 800.521.0574 •