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SOLVING BIOLOGY’S MYSTERIES USING QUANTUM MECHANICS There’s a fine line between being hailed as a visionary and being denounced as a crank, as Iraq-born physicist Jim Al-Khalili is only too aware. Seated in his office at the University of Surrey in the U.K. on a sunny day, he recalls a less tranquil time in his career, almost 15 years ago. Back then, he and his Surrey colleague, biologist Johnjoe McFadden, explored a strange mechanism to explain how DNA — the molecule that carries our genetic code — may mutate. at the time, their paper was one of the first in the now burgeoning field of quantum biology. The strange rules that control the subatomic world might be unintuitive, but they have been verified through many experiments for the better part of a century. Yet it is only in the past Their theory caused a stir because it invoked quantum mechanics, the branch of physics that describes the behavior of particles in the subatomic realm. Their idea gave some insight into the origins of genetic mutations, which over the centuries have given rise to the variety of species in the biological kingdom, and in the short term can lead to the development of diseases like cancer. The proposal was scoffed at, however, sparking incredulity from both biologists and physicists because quantum effects supposedly hold sway only on the smallest scales and cannot govern large biological molecules. “Senior colleagues in physics warned me off this line of research, saying, ‘This isn’t just speculative, it’s wacky,’ ” Al-Khalili says. “I have since realized that some of the best ideas come out of seemingly crazy thoughts, because otherwise they wouldn’t be new.” Though Al-Khalili and McFadden did not label it as such decade or so that a small but dedicated band of physicists and biologists has found hints that nature may also use these rules to enhance the efficiency of biological tasks. If true, then physicists struggling to innovate in the lab could take a quantum leaf out of nature’s book and learn how to devise better machines. Even more ambitiously — and controversially — some argue that quantum biology could be a game-changer in treating serious diseases. “The holy grail is to find that quantum effects stimulate biological processes that are relevant to medicine,” says Al-Khalili. “Looking to the long term, if these effects underlie the mechanism of DNA mutations, that could allow for real progress in the treatment of cancer.” Reference: Merali, Z. (2014, December 29). Solving Biology’s Mysteries Using Quantum Mechanics. Retrived from arihinde Discover Magazine: http:// discovermagazine.com/2014/dec/17-this-quantumlife on May 10, 2017 64 THE CLAPPER 2016 - 2017