THE ANTIFUNGAL EFFECT OF DIFFERENT
CONCENTRATIONS OF OIL SOLUTIONS OF
CYMBOPOGON CITRATES AND COCOS NUCIFERA
AGAINST CANDIDA ALBICANS
The identified funguson people who suffer from diaper
rash was opportunistic Candida albicans which commonly
occurs as a harmless commensal on human micro
flora but occasionally causes secondary skin infections
-if not treated-especially in immunocompromised
C.citratus oil solutions on Candida albicans was
investigated within a comparison to protect people
suffering from diaper rash from possible C.albicans
infections by using new and natural supportive care
methods from C.nucifera and C.citratus was aimed.
During the investigation, Candida albicans sample
was taken from Atatürk University Department of
Microbiology, C.nucifera and C.citratus oils were
obtained commercially and then disc diffusion method
was applied with seven different concentrations of
both oil solutions on inoculated nutrient agar with
10 -4 CFU ml -1 C.albicans and incubated at 37ºC for
48 hours. The data results showed that oil solutions
of C.citratus and C.nucifera -diluted by DMSO-
BIOLOGY
DEPARTMENT
patients. Although antifungal creams widely use
important biochemicals in order to treat or prevent the
infections; due to increasing development of antifungal
resistance and the appearance of undesirable side
effects, antifungal activities have been emphasized
more frequently in a wide range of essential oils and
natural products in an attempt to discover new antiinfective
agents.Also, recent studies showed that
gram positive strain of C.albicans gained resistance
against frequently used fluconazole antifungal agents
(Marchaim et al, 2012). Thus, in this experiment
the antifungal effect of different concentrations
(1%,2%,4%,8%,16%,32%,64%) of C.nucifera and
have antifungal activity against C.albicans and for
each seven concentration C.citratus demonstrated
higher inhibition zone diameter in average against
C.albicans such as respectively 6.1-8.3 mm for 1%;
6.6-8.3mm for 2%; 7.5-9.5mm for 4%; 8.6-10.1mm
for 8%; 9.3-11.8mm for 16%; 10.3-13.9mm for 32%;
11.3-14.7mm for 64%.In that point, the difference
between antifungal activities of C.nucifera and
C.citratus were supported with One-way ANOVA test
in SPSS 21.0 program since p<0.5.
Hazal KIZILKAYA
12-B
THE CLAPPER 2016 - 2017 63