2015 Brain Aneurysm Foundation Annual Report 2015-Brain-Aneurysm-Foundation-Annual-Report | Page 5

2015 RESEARCH GRANTS In 2015, the Brain Aneurysm Foundation awarded thirteen grants totaling $265,000 supporting our commitment to invest in brain aneurysm research. The Brain Aneurysm Foundation awards research grants for basic scientific research directed at early detection, improved treatment modalities, and technological advances that will ultimately improve outcomes for patients with brain aneurysms. The foundation’s Research Grant Committee is headed by Robert Rosenwasser, MD, FACS, Professor of Radiology and Neurosurgery at Thomas Jefferson University Hospital. He, along with other members of the Medical Advisory Board, scores all grant applications to determine the grant recipients based on the highest scores. William Gibson, MD, The University of British Columbia, Child & Family Research Institute Cynthia Lynn Sherwin Chair of Research: $25,000 Awarded for: Exome Sequencing Study of Dominant Mutations in Familial Brain Aneurysms Itender Singh, MD, Washington University in St. Louis North Shore University Hospital Brain Aneurysm Center Chair of Research: $25,000 Awarded for: The Role of Cyclophilin A in Blood-­rain Barrier, Neurionflammation and Vasospasm after Subarachnoid Hemorrhage Justin M. Caplan, MD, Johns Hopkins University School of Medicine Step for Hope Chair of Research: $25,000 Awarded for: The Role of Neural Stem Cells in Learning and Memory in Experimental Subarachnoid Hemorrhage Ashish Sonig, MD, University at Buffalo The Shirley Dudek Demmer Chair of Research: $25,000 Awarded for: MicroRNA in Unruptured Intracranial Aneurysms: Fostering a Mechanism of Early Detection Koji Hosaka, PhD, University of Florida Kristen’s Legacy of Love Chair of Research: $20,000 Awarded for: Mechanism of Aneurysm Progression and Healing: Differential Roles of Macrophages in Distinct Phases of Inflammation Kimberly P. Kicielinski, MD, University of Alabama at Birmingham The Maine’s KAT Walk & Karo-­5K Chair of Research: $25,000 Awarded for: Correlation of Cerebral Aneurysm Wall Structure on OCT Images with Flow Models of Wall Shear Stress: A Pilot Study Aichi Chien, PhD, The Regents of the University of California, Los Angeles Timothy P. Susco Chair of Research: $25,000 Award for: Longitudinal Analysis of Aneurysm 3D Morphology Changes and their Influence on Rupture Risk in Clinically followed Growing Aneurysms Douglas J . Cook, MD, Queens University The Ellie Helton Chair of Research: $15,000 Awarded for: Probing the Link between Indolent Aneurysmal Dome Infection and Brain Aneurysm Growth and Rupture Hui Meng, PhD, The State University of New York at Buffalo The Carol W. Harvey Memorial Chair of Research: $25,000 TeamCindy – Alcatraz Chair of Research: $10,000 Awarded for: Development of Blood-­Based Biomarkers for Brain Aneurysm Detection: Stage II Model Development Christoph J . Griessenauer, MD, Beth Israel Deaconess Medical Center The Doris A. Connor Memorial Chair of Research: $15,000 Awarded for: The Role of Anti-­Angiogenic Factors Soluble Fms-­Like Tyrosine Kinase-­1 (sFlt-­1) and Soluble Transforming Growth Factor B (TGFB) Co-­Receptor Endoglin (sEng) in the Pathophysiology of Delayed Cerebral Ischemia Jung M. Park, MD PhD student, University of Iowa Karen M. Schurr Memorial Chair of Research: $10,000 Awarded for: The Role of Inflammation and Myeloperoxidase in Cerebral Aneurysm Formation and Rupture Mohammad Amin Adibi, University of Calgary Christopher C. Getch Chair of Research (sponsored by the CV Section): $10,000 Awarded for: Intravenous Mesenchymal Stem Cell Therapy on Aneurysm Formation in a Rabbit Model Shakira Brathwaite, St. Michael’s Hospital Dawn Brejcha Chair of Research: $10,000 Awarded for: Role of Toll-­like Receptor 4 Signaling in Experimental Subarachnoid Hemorrhage Brain Aneurysm Foundation | 5