Montgomery County Community College( Guest Presenters)
Joshu’ wa Reid( In) Exploring Quantum Materials: Classifying and Analyzing Novel Candidates for Quantum Information Science Quantum Information Science is emerging as a key field in nanotechnology, with the potential to transform computation, data analysis, and simulation through use of qubits. Researchers have traditionally relied on the use of specific semiconductors to‘ manufacture’ qubits owing to its engineering and fine-tuning capabilities. However, several other materials are now being explored as potential alternatives on the basis of their inherent properties and potential to modify how they are grown or doped. This study provides a comprehensive analysis and categorization of various materials being investigated for their unique characteristics and potential applications in quantum information.
Sihem Nadour, Kayla Clement, Hetal Doshi, Dr. Maggie Bryans( P) Assessing the Stability of NISTCHO Cells in Long-Term Culture Chinese hamster ovary( CHO) cells are widely used in biopharmaceutical production due to their strong protein expression capabilities. The NISTCHO cell line, developed by the National Institute of Standards and Technology( NIST), serves as a standardized reference material for the biopharmaceutical industry. NISTCHO cells produce the monoclonal antibody cNISTmAb, which targets the surface glycoprotein F of the Respiratory Syncytial Virus( RSV). In this study, we evaluated the growth profiles and monoclonal antibody production of NISTCHO cells over long-term culture, encompassing more than one hundred cell doublings. [ Link to Poster Presentation ]
Joseph Toczydlowski, Hetal Doshi, Dr. Maggie Bryans( P) Presentation Title: Investigation and Comparison of Doubling Times in CHOZN and NISTCHO Cells CHOZN and NISTCHO are Chinese hamster ovary cell lines developed by Millipore Sigma and NIST, respectively. CHOZN cells were engineered by silencing the glutamine synthetase( GS) gene, providing a mechanism for recombinant cell selection. NISTCHO was created by transfecting genes for a monoclonal antibody with the GS gene into CHOZN cells. Preliminary studies indicated a longer doubling time for NISTCHO potentially due to the increased metabolic burden of glutamine production. This hypothesis was tested by establishing the doubling time for both cell lines then examining the effect of glutamine on NISTCHO proliferation and performance by culturing in medium plus / minus glutamine. 29